Abstract: The application of Pentacam AXL in cataract, glaucoma, keratoconus and orthokeratology is increasing year by year. It can guide to optimize IOL (for example, choosing astigmatism correction IOL according to the total corneal astigmatism, choosing IOL according to the total corneal spherical aberration, choosing the multifocal IOL according to the kappa angle), calculate the IOL degrees (using the total corneal refraction power to calculate the true corneal curvature, measuring the axial length according to PCI) for cataract patients, and evaluate the progress of cataract (according to the Pentacam nucleus system). It can also monitor the structure of the chamber angle and the central cornea thickness, screen the subclinical keratoconus, monitor the changes of the cornea after corneal cross-linking, and monitor the wearing of the orthokeratology. However, Pentacam AXL can not monitor fixation, has low recognition of IOL, and only provides the formula of diopter of astigmatism correction IOL and is easily affected by tear film.(Int Rev Ophthalmol, 2020, 44: 214-Post insert Ⅱ)